The factors analyzed and defined in the two briefs, HCMB and HCBB, can also be used to describe the characteristics of existing buildings and real estate complexes. This application of a multifactorial matrices indicates their state of health, as well as the strengths and weaknesses to address.

Creating an urban environment that fosters a sense of community, solidarity, and collaboration is essential. Urban design can play a major role in protecting both mental and physical health, and enhancing those outcomes capable to allign design with expected environmental features.

The brief is structured in four distinct phases, progressively mitigating environmental, psychological, and neurobiological risk factors encountered by individuals and communities. We spend more than 90% of our life indoor, so a good design can be very beneficial.

Measuring and monitoring the results of these applications is central to real estate developments and to supporting new activities. Data are needed to asses the final gain. Various methods are employed, both in situ and in the laboratory, such as observation, questionnaires, and neurophysiological tools.